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Sigma
Nitrosomorpholine
N7382
DOWNLOAD MSDS (PDF)CAS Number: 59-89-2
Empirical Formula (Hill Notation): C4H8N2O2
Molecular Weight: 116.12
MDL number: MFCD00039710
PubChem Substance ID: 24897824
Description
Biochem/physiol Actions
Tumor initiator in rodent liver, trachea, nasal cavity, esophagus, kidney, lung, and thyroid.1,2
Packaging
1, 5 mL in glass btl
Bulk package
Price and Availability
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Safety Information
| Symbol |   GHS06, GHS08 |
| Signal word | Danger |
| Hazard statements | H301-H351 |
| Precautionary statements | P281-P301 + P310 |
| Personal Protective Equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn |
| Risk Statements | 22-40 |
| Safety Statements | 36/37 |
| RIDADR | UN 2810 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | QE7525000 |
Technical information & documentation associated with this product is available in the Safety & Documentation tab.
Articles
Carcinogenesis and Epigenetics
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
Vicki Caligur
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Transcription, transformation
References
1. Lijinsky, W. and Reuber, M.D., Comparative carcinogenesis by nitrosomorpholines, nitrosooxazolidines and nitrosotetrahydrooxazine in rats. Carcinogenesis 3, 911-915, (1982) Abstract
2. Lijinsky, W. et al., Carcinogenesis in rats by substituted dialkylnitrosamines given by gavage. In Vivo 5, 85-89, (1991) Abstract
Merck 14,6640
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